Beovu Pre-filled Syringe

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Uses of Beovu Pre-filled Syringe

Beovu Pre-filled Syringe is made from a human antibody fragment. It works by keeping new blood vessels from forming under the retina (a sensory membrane that lines the inside of the eye). In people with certain types of eye disorders, new blood vessels grow under the retina where they leak blood and fluid.

Brolucizumab ophthalmic (for the eyes) is used to treat the “wet form” of age-related macular degeneration.

Precautions and Warnings

You should not use brolucizumab if you are allergic to it, or if you have:

  • inflammation inside your eye; or
  • an infection in or around your eye.

Tell your doctor if you have ever had:

  • glaucoma;
  • cataracts; or
  • a stroke.

Do not use brolucizumab if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are receiving brolucizumab ophthalmic and for at least 1 month after your last dose.

Do not breastfeed while receiving this medicine, and for at least 1 month after your last dose.

Dosage

 Neovascular Age-Related Macular Degeneration: The recommended dose for BEOVU is 6 mg (0.05 mL of 120 mg/mL solution) administered by intravitreal injection monthly (approximately every 25 to 31 days) for the first three doses, followed by 6 mg (0.05 mL) by intravitreal injection once every 8 to 12 weeks.

Diabetic Macular Edema: The recommended dose for BEOVU is 6 mg (0.05 mL of 120 mg/mL solution) administered by intravitreal injection every six weeks (approximately every 39-45 days) for the first five doses, followed by 6 mg (0.05 mL) by intravitreal injection once every 8-12 weeks.

Side Effects

Common side effects:

  • blurred vision, hazy vision;
  • increased sensitivity to light;
  • eye pain; or
  • seeing floaters.

Serious side effects:

  • eye pain or redness, swelling around your eyes;
  • discharge or bleeding from the eye;
  • seeing “floaters” in your vision;
  • increased sensitivity to light;
  • decreased vision, tunnel vision, or seeing halos around lights; or
  • sudden numbness or weakness, problems with speech or balance.

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