Identifying the Core Origins of Depression

Post written by BH Staff Writer on May 16, 2023
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**What Triggers Depression?**

Depression is a mental health condition that impacts millions of people around the globe. According to the World Health Organization (WHO), over 264 million individuals of all ages grapple with depression worldwide. Despite its prevalence, the precise causes of depression remain somewhat unclear.

This article delves into the various factors that can lead to depression.

Factors Contributing to Depression

Genetics

Studies indicate that genetics significantly impact the likelihood of developing depression. Research shows that if you have a close family member with depression, your chances of developing the condition increase.

Recent findings have identified specific genes that may heighten the risk of depression. One such gene is the serotonin transporter gene, which regulates serotonin levels in the brain. Serotonin is a neurotransmitter pivotal in mood regulation, and an imbalance in its levels can lead to depressive states.

Further, variations in the gene that encodes the brain-derived neurotrophic factor (BDNF) protein are associated with a heightened risk of depression. BDNF supports neuron survival and growth in the brain, and low levels of BDNF are linked to depression.

Brain Chemistry

An imbalance of certain brain chemicals, including serotonin, dopamine, and norepinephrine, also plays a critical role in depression. These neurotransmitters help regulate mood, and when their levels are imbalanced, symptoms such as sadness and hopelessness can occur.

Life Events

Stressful life events like divorce, job loss, or the death of a loved one can significantly contribute to depression. Studies indicate that individuals experiencing these life-altering events are more likely to develop depression than those who do not.

Medical Conditions

Chronic illnesses such as cancer, diabetes, and heart disease can exert immense physical and emotional stress, potentially leading to depression. Moreover, some medications prescribed for these conditions may have depression as a side effect.

Substance Abuse

The use of alcohol and drugs can disrupt the brain’s chemical balance, leading to depressive symptoms. Social studies reveal that those struggling with substance abuse may also face financial and legal issues, exacerbating feelings of depression.

Social Factors

Individuals facing social difficulties such as poverty, isolation, or discrimination are at a higher risk of developing depression. Social support and understanding are crucial for the recovery of people in these situations.

For more information about mental health and support services, visit Bridge Health.

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