### Asacol vs Pentasa: What Differentiate Pentasa and [Asacol](https://bridgecanhealth.com/prescription-drugs/asacol/)?
Pentasa (mesalamine) and Asacol (mesalamine) are both anti-inflammatory medications designed to treat proctitis, proctosigmoiditis, and ulcerative colitis. They are also employed to help prevent the recurrence of symptoms associated with ulcerative colitis. Despite their similarities, there are subtle differences that set these two drugs apart.
Both medications contain mesalamine, which works to reduce inflammation in the bowel. However, the primary distinctions lie in their formulation and release mechanisms. Let’s delve into these differences.
## **What is Asacol?**
[Asacol](https://bridgecanhealth.com/prescription-drugs/asacol/) (mesalamine) is a medication mainly utilized for treating ulcerative colitis and other inflammatory bowel conditions. It is also effective in preventing inflammations such as proctitis and proctosigmoiditis.
This drug helps manage symptoms of ulcerative colitis, including abdominal pain, rectal bleeding, and diarrhea. Asacol contains mesalamine, which is part of the aminosalicylates class of drugs, known for their anti-inflammatory properties.
## **Asacol Side Effects**
Possible side effects while taking [Asacol](https://bridgecanhealth.com/prescription-drugs/asacol/) include:
- Headache
- Nausea
- Cold symptoms (runny nose, sore throat)
- Abdominal pain
- Diarrhea
- Indigestion
- Gas
- Flu-like symptoms
- Fever
- Cough
Most of these mild side effects may resolve on their own within a few days to weeks. However, if they continue or interfere with your daily activities, it’s advisable to consult your doctor or pharmacist.
## **What is Pentasa?**
Pentasa, another mesalamine-based medication, is FDA-approved for treating ulcerative colitis in adults.
Ulcerative colitis involves inflammation of the lining of the colon and rectum, causing ulcer formations. It’s a chronic condition with fluctuating symptoms, including periods of active flare-ups and remission.
Pentasa is notably recommended for:
- Inducing remission in ulcerative colitis
- Treating mild to moderate ulcerative colitis
## **Pentasa Side Effects**
Mild side effects from Pentasa may include:
- Joint pain
- Diarrhea
- Nausea and vomiting
- Abdominal pain
- Upset stomach
- Headache
- Hair loss
These side effects typically subside within a few days to weeks. If they persist or worsen, consult your doctor or pharmacist.
Serious side effects of Pentasa include:
- Liver issues: Symptoms can include jaundice and upper right abdominal pain.
- Kidney problems: Symptoms might include swollen legs, ankles, or feet, decreased urination, nausea, confusion, shortness of breath, and fatigue.
- Mesalamine-induced acute intolerance syndrome: This may manifest with symptoms similar to ulcerative colitis flare-ups, such as stomach cramps, fever, headache, skin rash, and bloody diarrhea.
- Severe skin rashes
- Bloody stools
- Worsened allergic reactions
Always seek medical advice from your healthcare provider if you experience any serious side effects.