Why Is Combigan Priced So Expensively?

Post written by BH Staff Writer on July 24, 2023
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Why Is Combigan So Expensive? Combigan, a commonly prescribed medication for treating glaucoma, is celebrated for its effectiveness but is also notorious for its high price. Patients and healthcare professionals often wonder why this drug is so costly. In this article, we’ll delve into the factors contributing to the steep cost of Combigan and explore why it remains an expensive choice for many patients.

The Cost of Combigan

Numerous individuals in the United States are turning to Bridge Health to purchase their Combigan due to its high retail prices. One patient, who preferred to stay anonymous, shared, “Affording Combigan is a struggle. Its high cost places a financial burden on my family and me. I rely on Bridge Health, as it drastically lowers my expenses.” The average retail cost for a 5ml bottle of Combigan in the U.S. ranges from $200 to $250, depending on the region and pharmacy. However, at Bridge Health, it is priced at $79.99. The patient added, “It doesn’t matter whether I get the medication from Canada or elsewhere, as long as it’s reliable and affordable. When you’re in need, you find ways to manage within your means.”

What do doctors say about the high costs of Combigan in the U.S.? Dr. Lisa Pereira, a physician, stated, “As a healthcare provider, it’s challenging to see patients struggle with high medication costs. It affects their ability to access essential treatments and negatively impacts their overall health outcomes. Some patients may opt for the generic version, Brimonidine Tartrate-Timolol, due to its affordability, but others depend on brand-name medications and bear the financial burden.”

It is important to understand that drug prices are influenced by factors including market demand, manufacturing costs, research and development investments, and the intricacies of the healthcare system within which the medication is distributed. An ex-employee of Novartis said, “The cost of developing and manufacturing medications is a complex process involving significant investments in research, clinical trials, and production. These costs contribute to the final price.” Combigan is no exception.

Factors Driving the High Cost

  1. Research and Development Costs: Developing new medications involves substantial investments in research, clinical trials, and obtaining regulatory approvals. Pharmaceutical companies often spend billions and years to bring a drug to market. These expenses significantly contribute to the final price of the medication.
  2. Manufacturing Expenses: The manufacturing process for pharmaceuticals is intricate and requires adherence to stringent quality control measures, facility maintenance, and regulatory guidelines. These factors add to the overall manufacturing expenses, which are passed on to consumers.
  3. Patent Protection and Exclusivity: When a pharmaceutical company discovers and develops a new drug, they are granted a patent, allowing them exclusive rights to manufacture and sell the medication for a specified period. This exclusivity allows companies to recoup their investments and earn a profit. During this time, generic versions are unavailable, maintaining high prices. Once the patent expires, generic competitors can enter the market, often reducing prices.
  4. Limited Market Competition: Combigan combines two active ingredients, brimonidine tartrate and timolol maleate. The limited number of competitors producing a similar combination restricts competitive pressure on the price. The absence of direct alternatives permits pharmaceutical companies to maintain higher pricing levels.
  5. Marketing and Advertising: Significant expenditures on marketing and advertising to promote medications also contribute to higher prices, as these costs are often passed on to consumers.
  6. Insurance Coverage and Negotiations: Insurance companies and pharmacy benefit managers (PBMs) play a critical role in drug pricing. Coverage and negotiations between pharmaceutical manufacturers and insurers affect the final price for patients. The complex nature of these negotiations, including rebates and discounts, can impact medication costs.
  7. Distribution and Supply Chain: Medications pass through a complex supply chain involving wholesalers, distributors, and pharmacies, each adding their markup to the final price. These markups significantly affect the medication cost for patients.

The high cost of Combigan results from a combination of these factors.

While the high cost of Combigan may be burdensome to patients, it’s essential to understand the factors contributing to its expense. Patients should consult their healthcare providers and explore potential options to manage the financial aspects of their treatment without compromising their health.

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