Effects of Off-Label Ozempic Usage for Weight Loss

Post written by BH Staff Writer on April 10, 2023
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Over recent months, the spotlight has turned to Ozempic, not for its prescribed use in managing type 2 diabetes, but for its off-label application as a weight loss solution. Once a relatively lesser-known type 2 diabetes medication—initially ranking 129th on the list of most prescribed drugs—Ozempic’s sales have surged globally by an incredible 111% in the last few months. What has fueled this sudden rise in popularity, and what does this mean for those who use Ozempic? Let’s explore these questions in detail.

In 2022, a groundbreaking study involving a group of obese adolescents demonstrated that a weekly dose of 2.4mg of Ozempic led to a substantial reduction in both weight and body mass index. This discovery has completely altered public perception of the drug. However, it’s crucial to remember that neither the manufacturer, Novo Nordisk, nor the FDA, endorse or certify the safety of Ozempic for off-label use as a weight loss medication.

Media reports have brought to light four primary side effects linked to Ozempic. Let’s take a closer look:

  1. Mental Health Decline: Some users have reported experiences of depression and anxiety. The active ingredient in Ozempic, GLP-1, can operate differently in non-diabetics, potentially affecting the brain or central nervous system.
  2. “Ozempic Face”: This term has been coined after several users, particularly younger individuals, noticed a “gaunt, deflated, and saggy face.” Rapid fat loss from the body, including the face, can cause an unhealthy and sickly appearance.
  3. The Rebound Effect: A significant concern is the rapid weight regain when discontinuing Ozempic. Many users report putting the weight back on within just a few days. Novo Nordisk has acknowledged in interviews that they did not investigate Ozempic’s rebound effect.
  4. Worsening Pre-existing Conditions: Individuals with pre-existing kidney, gallbladder, or vision issues have noticed a further decline in their conditions.

While many conventional doctors still recommend the proven benefits of a balanced diet paired with regular exercise for effective and safe weight loss, some physicians prescribing Ozempic for this purpose stress the importance of professional support from psychiatrists and dietitians to help manage potential side effects.

Therefore, we pose an essential question: Is the pursuit of weight loss worth risking mental health and exposing oneself to an array of side effects? Or is it more prudent to adopt the reliable methods of healthy eating and increased physical activity?

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