## Asacol vs. Lialda: Comparing Aminosalicylate Medications for Ulcerative Colitis
Asacol and Lialda are two prevalent anti-inflammatory aminosalicylate medications prescribed to treat conditions like ulcerative colitis, proctitis, and proctosigmoiditis. These medications are also utilized to help prevent the recurrence of symptoms in patients with ulcerative colitis.
Ulcerative colitis is a chronic condition characterized by prolonged duration. Symptoms can fluctuate, featuring periods of active symptoms known as flare-ups, and phases where symptoms are minimal or absent, termed remission.
So, what sets Asacol apart from Lialda? Is one medication superior to the other? Continue reading for a detailed comparison of these two treatments.
### What is Asacol?
Asacol is prescribed for certain intestinal conditions such as ulcerative colitis. It aids in alleviating symptoms including stomach discomfort, rectal bleeding, and diarrhea. The active ingredient in Asacol is Mesalamine, a member of the aminosalicylate drug class.
Asacol is often used as a maintenance therapy to sustain remission, which is characterized by minimal or no disease activity, and is not intended to suppress flare-ups of active disease. It is not suitable for patients with moderate to severe ulcerative colitis who have reached remission through biologic and immunomodulatory medications.
### How is Asacol Taken?
Asacol can be administered orally, topically, or as a liquid or foam enema. The tablets should be swallowed whole—not crushed or chewed—to be effective. The pill’s outer shell is safe for ingestion and is fully absorbed by the body.
### Asacol Side Effects
Common side effects of Asacol include:
- persistent stomach ache
- stomach cramps
- bloody stool
- fever
- headache
- body rash
- stools resembling coffee grounds
- reduced or difficult urination
- swollen ankles and feet
- fatigue
- difficulty breathing
- decreased appetite
- upper stomach discomfort
- easy bruising or bleeding
- dark urine
- jaundice
### What is Lialda?
Similar to Asacol, Lialda is an anti-inflammatory medication utilized to manage ulcerative colitis and other inflammatory bowel diseases. It also contains Mesalamine and belongs to the aminosalicylate drug class, helping to reduce bowel inflammation.
Lialda is usually administered as a delayed-release tablet taken once daily with a meal. Each tablet is 1.2 grams, and no other strengths are available.
### How is Lialda Taken?
It is crucial to follow your doctor’s instructions when taking Lialda. The medication needs to be swallowed whole, not chewed, crushed, or broken, to ensure proper absorption in the colon. Dosage is based on your medical condition and response to treatment. For children, the dosage may also be weight-based.
### Lialda Side Effects
Common side effects of Lialda include:
- headache
- flatulence (passing gas)
- elevated liver enzyme levels
- stomach/belly ache
- diarrhea
- hair loss
- joint pain
- dizziness
- upper respiratory infection, such as the common cold
- vomiting
- anemia (low red blood cell levels)
- nausea
This comparison aims to provide an overview of Asacol and Lialda, offering insights into their use, administration, and potential side effects. Always consult your healthcare provider for personalized medical advice tailored to your condition.