Ramipril and Lisinopril are highly effective medications for managing hypertension and supporting heart and kidney health. Individuals struggling with high blood pressure often rely on these drugs to prevent serious complications. Both medications belong to the angiotensin-converting enzyme (ACE) inhibitors class, which helps relax blood vessels and lower blood pressure.
So, what differentiates Ramipril from Lisinopril? Read on to discover the nuances between these two medications.
Ramipril vs. Lisinopril: A Comparison
Ramipril and Lisinopril share more similarities than differences. Both are ACE inhibitors, offering almost identical advantages and side effects to patients.
However, Ramipril is noted for the lowest rate of all-cause mortality, while Lisinopril has been shown to be less effective in reducing systolic and diastolic blood pressure. Additionally, Lisinopril is associated with a higher incidence of all-cause mortality compared to Ramipril.
Understanding Ramipril
Ramipril is prescribed for treating high blood pressure and also reduces the risk of death, heart attacks, and strokes. It can be used for patients recovering from a heart attack to manage heart failure.
Ramipril is available both as a generic and under the brand name Altace.
Possible side effects include sudden swelling of the face, arms, legs, lips, tongue, throat, and intestines. If you experience stomach pain or swelling in these areas while taking Ramipril, discontinue use immediately and consult your doctor.
Understanding Lisinopril
Like Ramipril, Lisinopril is used to treat high blood pressure, lowering it to healthy levels and reducing the risk of heart attacks, kidney problems, and strokes. Lisinopril also aids patients in living longer after a heart attack and is used for treating heart failure by relaxing blood vessels and improving blood flow.
It is recommended to take your first dose of Lisinopril at bedtime due to potential dizziness. If you do not experience dizziness after the first dose, you can take it at any consistent time during the day.
How ACE Inhibitors Work
ACE inhibitors are cardiovascular medications that help to widen blood vessels, reducing blood pressure. They also increase the amount of blood your heart pumps, thereby alleviating stress on the heart and enhancing blood flow.
Other uses for ACE inhibitors include:
- Coronary artery disease
- Heart failure
- Diabetes
- Certain chronic kidney diseases
- Heart attacks
- Scleroderma
- Migraines
ACE inhibitors are sometimes used in conjunction with other blood pressure medications like diuretics or calcium channel blockers. However, it’s crucial to avoid using ACE inhibitors alongside angiotensin receptor blockers or direct renin inhibitors.