Best Antidepressants to Use in Combination with Abilify

Post written by BH Staff Writer on November 23, 2022
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### Optimal Antidepressant Combinations with Abilify: A Comprehensive Guide

Many adults dealing with major depressive disorder find that standard antidepressants alone aren’t always enough. In such instances, incorporating Abilify can enhance the effectiveness of traditional antidepressant therapies.

Antidepressants are widely prescribed to treat conditions like anxiety and depression. According to data from the Centers for Disease Control and Prevention (CDC), 13.2% of American adults used antidepressant medications during a 30-day period in a study conducted from 2015 to 2018.

While antidepressants have considerably aided in managing depression and anxiety, some individuals may still require additional support. Adding medications like Abilify to a treatment plan can potentially amplify the overall effectiveness.

Continue reading to learn about the most effective antidepressants to pair with Abilify.

Combining Abilify and Antidepressants

Abilify can be used independently to treat various mental health conditions. However, its efficiency in treating depression often reaches its peak when combined with other medications, especially antidepressants.

Research suggests that antidepressants, although primarily designed to treat depression, achieve remission in only about one-third of patients. The remaining two-thirds often need supplementary treatments for effective symptom management.

Adding Abilify to an existing treatment regimen frequently results in better outcomes compared to using a single antidepressant alone.

Which Antidepressants Work Well with Abilify?

Serotonin and norepinephrine reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs) are categories of antidepressants that, when combined with Abilify, can manage depression more effectively.

Below are some of the best antidepressants to pair with Abilify:

  • fluoxetine (Prozac)
  • sertraline (Zoloft)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)
  • citalopram (Celexa)
  • fluvoxamine (Luvox)
  • vilazodone (Viibryd)
  • duloxetine (Cymbalta)
  • venlafaxine (Effexor)
  • desvenlafaxine (Pristiq)
  • levomilnacipran (Fetzima)

Note: Although more extensive research is needed on the combination of Abilify (Aripiprazole) with specific antidepressants, some studies indicate that pairing Lexapro with Abilify might be particularly effective in treating depression.

Medications to Avoid When Taking Abilify

Abilify can cause adverse reactions when combined with certain drugs, potentially leading to serious complications. Medications that may negatively interact with Abilify include:

  • metoclopramide
  • Adderall
  • clarithromycin
  • itraconazole
  • quinidine
  • Prozac
  • Paxil
  • carbamazepine
  • rifampin
  • lorazepam

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