Prolia Prefilled Syringe

Please note: a valid prescription is required for all prescription medication.

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Uses of Prolia Prefilled Syringe

Prolia (denosumab) is commonly used to treat osteoporosis, a condition in which the bones are thinner, weaker, and more prone to breakage. Prolia may be prescribed for people at high risk for fractures in the following situations.

  • Postmenopausal people with osteoporosis
  • People who take a medicine called a corticosteroid such as prednisone

Prolia is also used to increase bone mass in people at high risk for fracture in men with osteoporosis and people who take certain medicines for either breast or prostate cancer.

Precautions and Warnings

Do not use Prolia unless it has been prescribed to you by a healthcare provider. Use it as prescribed.

Do not share Prolia with other people, even if they have the same condition as you. It may harm them.

Do not shake Prolia.

Brush and floss your teeth daily. Tell your dentist you are using Prolia before having any dental work done.

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Prolia is right for you.

In particular, make sure that you discuss any of the following.

If you have advanced chronic kidney disease or are receiving dialysis, you are at greater risk for low blood calcium.

Do not take Prolia, and tell your healthcare provider if you are or plan to become pregnant. Prolia may cause harm to your unborn baby. If you can become pregnant, you must use contraception during Prolia treatment and for 5 months after stopping Prolia. Your healthcare provider will make sure you have a negative pregnancy test before starting Prolia.

Prolia should not be used if you are breastfeeding. It is not known if Prolia passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should stop breastfeeding or stop Prolia.

Dosage

The recommended dose is 60 mg denosumab administered as a single subcutaneous injection once every 6 months into the thigh, abdomen or upper arm.

Side Effects

Common side effects:

  • Back pain, muscle pain, joint pain, or pain in the arms and legs
  • High cholesterol levels
  • Bladder infection
  • High blood pressure
  • Headache
  • Bronchitis
  • Runny nose or sore throat

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